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HBV Target gene Detail Information

> IL10 Gene Search Result


Gene Information
Gene Name IL10
Gene ID 3586
Gene Full Name interleukin 10
Gene Alias CSIF; TGIF; GVHDS; IL-10; IL10A
Transcripts ENSG00000136634
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P22301
HGNC ID HGNC:5962
VEGA ID OTTHUMG00000036386
OMIM ID 124092
String ID 9606.ENSP00000412237
Drugbank ID BE0002484
PharmGKB ID PA29778
Target gene [IL10] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 21168854 C1913A
C
G
C
 View
2 21168854 C2189A
C
G
C
 View
3 21168854 G1896A
PreC
G
C
 View
4 21168854 G2304A
C
G
C
 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of IL10 expression and immune infiltrating cell level correlation result in HBV+ samples
IL10 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).