HIV Target gene Detail Information

> IKZF4 Gene Search Result

Gene Information

Gene Name	IKZF4
Gene ID	64375
Gene Full Name	IKAROS family zinc finger 4
Gene Alias	EOS; ZNFN1A4
Transcripts	ENSG00000123411
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9H2S9
HGNC ID	HGNC:13179
VEGA ID	OTTHUMG00000170132
OMIM ID	606239
String ID	9606.ENSP00000262032
PharmGKB ID	PA162391948

Target gene [IKZF4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005480	chr12	9	22	1	32	View
4013578	chr12	3			3	View
4013579	chr12	3			3	View
4014681	chr12	2			2	View
4014849	chr12	2			2	View
4015245	chr12	1			1	View
4015246	chr12	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of IKZF4 expression and immune infiltrating cell level correlation result in HIV+ samples
IKZF4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).