HBV Target gene Detail Information

> IGSF21 Gene Search Result

Gene Information

Gene Name	IGSF21
Gene ID	84966
Gene Full Name	immunoglobin superfamily member 21
Transcripts	ENSG00000117154
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96ID5
HGNC ID	HGNC:28246
VEGA ID	OTTHUMG00000002432
String ID	9606.ENSP00000251296
PharmGKB ID	PA142671661

Target gene [IGSF21] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005064	chr1	13	31	18	62	View
1006031	chr1	13	21	10	44	View
1006875	chr1	31	2		33	View
1006876	chr1	31	2		33	View
1006915	chr1	15	14	3	32	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of IGSF21 expression and immune infiltrating cell level correlation result in HBV+ samples
IGSF21 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).