HBV Target gene Detail Information

> IGSF11 Gene Search Result

Gene Information

Gene Name	IGSF11
Gene ID	152404
Gene Full Name	immunoglobulin superfamily member 11
Gene Alias	CT119; VSIG3; Igsf13; BT-IgSF; CXADRL1
Transcripts	ENSG00000144847
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cell Junctions;Cytosol;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q5DX21
HGNC ID	HGNC:16669
VEGA ID	OTTHUMG00000159387
OMIM ID	608351
String ID	9606.ENSP00000377370
PharmGKB ID	PA134939253

Target gene [IGSF11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004941	chr3	53	12		65	View
1014420	chr3	3			3	View
1015247	chr3	2			2	View
1400411	chr3				0	View
1402884	chr3	53	12		65	View
1403008	chr3	2			2	View
1403009	chr3	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of IGSF11 expression and immune infiltrating cell level correlation result in HBV+ samples
IGSF11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).