HIV Target gene Detail Information

> IGF1R Gene Search Result

Gene Information

Gene Name	IGF1R
Gene ID	3480
Gene Full Name	insulin like growth factor 1 receptor
Gene Alias	IGFR; CD221; IGFIR; JTK13
Transcripts	ENSG00000140443
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins
Gene Function	Oncogene
Uniport_ID	P08069
HGNC ID	HGNC:5465
VEGA ID	OTTHUMG00000149851
OMIM ID	147370
String ID	9606.ENSP00000268035
Drugbank ID	BE0000858
PharmGKB ID	PA29698

Target gene [IGF1R] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010004	chr15	5	1	4	10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of IGF1R expression and immune infiltrating cell level correlation result in HIV+ samples
IGF1R expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).