HBV Target gene Detail Information

> IFNG Gene Search Result

Gene Information

Gene Name	IFNG
Gene ID	3458
Gene Full Name	interferon gamma
Gene Alias	IFG; IFI
Transcripts	ENSG00000111537
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins
Gene Function	Oncogene
Uniport_ID	P01579
HGNC ID	HGNC:5438
VEGA ID	OTTHUMG00000169113
OMIM ID	147570
String ID	9606.ENSP00000229135
Drugbank ID	BE0000944
PharmGKB ID	PA29674

Target gene [IFNG] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	14654974	A1762T	BCP	G C	View
2	30771531	G145R	S	C	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of IFNG expression and immune infiltrating cell level correlation result in HBV+ samples
IFNG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: LIHC