HBV Target gene Detail Information

> IFNAR1 Gene Search Result

Gene Information

Gene Name	IFNAR1
Gene ID	3454
Gene Full Name	interferon alpha and beta receptor subunit 1
Gene Alias	AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
Transcripts	ENSG00000142166
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P17181
HGNC ID	HGNC:5432
VEGA ID	OTTHUMG00000065126
OMIM ID	107450
String ID	9606.ENSP00000270139
Drugbank ID	BE0000661
PharmGKB ID	PA29670

Target gene [IFNAR1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008662	chr21	19	1		20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of IFNAR1 expression and immune infiltrating cell level correlation result in HBV+ samples
IFNAR1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).