HBV Target gene Detail Information

> IFNA2 Gene Search Result


Gene Information
Gene Name IFNA2
Gene ID 3440
Gene Full Name interferon alpha 2
Gene Alias IFNA; INFA2; IFNA2B; IFN-alphaA
Transcripts ENSG00000188379
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted secreted proteins
Uniport_ID P01563
HGNC ID HGNC:5423
VEGA ID OTTHUMG00000019674
OMIM ID 147562
String ID 9606.ENSP00000369554
Drugbank ID BE0003450
PharmGKB ID PA29662
Target gene [IFNA2] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 30095435 C1913A
C
C
View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of IFNA2 expression and immune infiltrating cell level correlation result in HBV+ samples
IFNA2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).