HBV Target gene Detail Information

> IFNA1 Gene Search Result

Gene Information

Gene Name	IFNA1
Gene ID	3439
Gene Full Name	interferon alpha 1
Gene Alias	IFL; IFN; IFNA@; IFNA13; IFN-ALPHA; IFN-alphaD
Transcripts	ENSG00000197919
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID	P01562
HGNC ID	HGNC:5417
VEGA ID	OTTHUMG00000019673
OMIM ID	147660
String ID	9606.ENSP00000276927
PharmGKB ID	PA29656

Target gene [IFNA1] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	26290395	C1653T	C Promoter	G S C	View
2	15720534	A1762T	BCP	G	View
3	20959021	I97L	C	D	View
4	24175223	A181T	RT	D	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of IFNA1 expression and immune infiltrating cell level correlation result in HBV+ samples
IFNA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: LIHC