HIV Target gene Detail Information

> ICE2 Gene Search Result

Gene Information

Gene Name	ICE2
Gene ID	79664
Gene Full Name	interactor of little elongation complex ELL subunit 2
Gene Alias	BRCC1; NARG2
Transcripts	ENSG00000128915
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q659A1
HGNC ID	HGNC:29885
VEGA ID	OTTHUMG00000132764
OMIM ID	610835
String ID	9606.ENSP00000261520
PharmGKB ID	PA134960292

Target gene [ICE2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002444	chr15	11	39	44	94	View
4005932	chr15	26	2		28	View
4008407	chr15	2	10	3	15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ICE2 expression and immune infiltrating cell level correlation result in HIV+ samples
ICE2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).