HBV Target gene Detail Information

> ICA1L Gene Search Result

Gene Information

Gene Name	ICA1L
Gene ID	130026
Gene Full Name	islet cell autoantigen 1 like
Gene Alias	ALS2CR14; ALS2CR15
Transcripts	ENSG00000163596
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8NDH6
HGNC ID	HGNC:14442
VEGA ID	OTTHUMG00000132856
String ID	9606.ENSP00000478645
PharmGKB ID	PA24738

Target gene [ICA1L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005112	chr2	25	36		61	View
1012334	chr2	5	2		7	View
1012491	chr2	2	4		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ICA1L expression and immune infiltrating cell level correlation result in HBV+ samples
ICA1L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).