Gene Information
Gene Name
|
HTRA2 |
Gene ID
|
27429
|
Gene Full Name
|
HtrA serine peptidase 2 |
Gene Alias
|
OMI; MGCA8; PARK13; PRSS25 |
Transcripts
|
ENSG00000115317
|
Virus
|
HTLV1 |
Gene Type
|
protein coding |
HPA Location Info
|
Mitochondria;
|
Membrane Info
|
Predicted membrane proteins |
HPA Protein Class Info
|
Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins |
Gene Function
|
Suppressor gene
|
Uniport_ID
|
O43464
|
HGNC ID
|
HGNC:14348
|
VEGA ID
|
OTTHUMG00000129957
|
OMIM ID
|
606441 |
String ID
|
9606.ENSP00000258080
|
PharmGKB ID
|
PA33836
|
Target gene [HTRA2] related to VISs
DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
6004580 |
chr2 |
111 |
|
|
111 |
View |
Relationship between gene expression and immune infiltrating cell level
Data ID |
Disease |
Sample number |
Sample type |
GSE55851 (GEO) |
Adult T-cell leukemia |
21 |
Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12) |
GSE29312 (GEO) |
HTLV-1 associated myelopathy |
39 |
Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10) |
GSE29332 (GEO) |
HTLV-1 associated myelopathy |
35 |
Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10) |
> Dataset: GSE55851
|
HeatMap of cell type fractions in all samples
|
Lollipop of HTRA2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
|
HTRA2 expression: Low -> High
|
|
|
> Dataset: GSE29312
|
HeatMap of cell type fractions in all samples
|
Lollipop of HTRA2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
|
HTRA2 expression: Low -> High
|
|
|
> Dataset: GSE29332
|
HeatMap of cell type fractions in all samples
|
Lollipop of HTRA2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
|
HTRA2 expression: Low -> High
|
|
|
|
|