HIV Target gene Detail Information

> HTR2B Gene Search Result

Gene Information

Gene Name	HTR2B
Gene ID	3357
Gene Full Name	5-hydroxytryptamine receptor 2B
Gene Alias	5-HT2B; 5-HT-2B; 5-HT(2B)
Transcripts	ENSG00000135914
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters
Uniport_ID	P41595
HGNC ID	HGNC:5294
VEGA ID	OTTHUMG00000133222
OMIM ID	601122
String ID	9606.ENSP00000258400
Drugbank ID	BE0000393; BE0004957
PharmGKB ID	PA29554

Target gene [HTR2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013805	chr2	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HTR2B expression and immune infiltrating cell level correlation result in HIV+ samples
HTR2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).