HBV Target gene Detail Information

> HTR2A Gene Search Result

Gene Information

Gene Name	HTR2A
Gene ID	3356
Gene Full Name	5-hydroxytryptamine receptor 2A
Gene Alias	HTR2; 5-HT2A
Transcripts	ENSG00000102468
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	P28223
HGNC ID	HGNC:5293
VEGA ID	OTTHUMG00000016881
OMIM ID	182135
String ID	9606.ENSP00000437737
Drugbank ID	BE0000451; BE0004957
PharmGKB ID	PA193

Target gene [HTR2A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003933	chr13	61	7	33	101	View
1404569	chr13	88	464	78	630	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of HTR2A expression and immune infiltrating cell level correlation result in HBV+ samples
HTR2A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).