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HBV Target gene Detail Information

> HSPA8 Gene Search Result


Gene Information
Gene Name HSPA8
Gene ID 3312
Gene Full Name heat shock protein family A (Hsp70) member 8
Gene Alias LAP1; HSC54; HSC70; HSC71; HSP71; HSP73; LAP-1; NIP71; HEL-33; HSPA10; HEL-S-72p
Transcripts ENSG00000109971
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P11142
HGNC ID HGNC:5241
VEGA ID OTTHUMG00000166030
OMIM ID 600816
String ID 9606.ENSP00000432083
Drugbank ID BE0003775
PharmGKB ID PA29507
Target gene [HSPA8] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
1001946 chr11 334 31 41 406 View
Showing 1 to 1 of 1 entries
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Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of HSPA8 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
HSPA8 expression: Low -> High
Lollipop of HSPA8 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of HSPA8 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of HSPA8 expression and immune infiltrating cell level correlation result in HBV+ samples
HSPA8 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).