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HBV Target gene Detail Information

> HSPA8 Gene Search Result


Gene Information
Gene Name HSPA8
Gene ID 3312
Gene Full Name heat shock protein family A (Hsp70) member 8
Gene Alias LAP1; HSC54; HSC70; HSC71; HSP71; HSP73; LAP-1; NIP71; HEL-33; HSPA10; HEL-S-72p
Transcripts ENSG00000109971
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P11142
HGNC ID HGNC:5241
VEGA ID OTTHUMG00000166030
OMIM ID 600816
String ID 9606.ENSP00000432083
Drugbank ID BE0003775
PharmGKB ID PA29507
Target gene [HSPA8] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001946 chr11 334 31 41 406 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of HSPA8 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
HSPA8 expression: Low -> High
Lollipop of HSPA8 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of HSPA8 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of HSPA8 expression and immune infiltrating cell level correlation result in HBV+ samples
HSPA8 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).