HIV Target gene Detail Information

> HSPA4 Gene Search Result

Gene Information

Gene Name	HSPA4
Gene ID	3308
Gene Full Name	heat shock protein family A (Hsp70) member 4
Gene Alias	RY; APG-2; HSPH2; hsp70; hsp70RY; HEL-S-5a; HS24/P52
Transcripts	ENSG00000170606
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	P34932
HGNC ID	HGNC:5237
VEGA ID	OTTHUMG00000129012
OMIM ID	601113
String ID	9606.ENSP00000302961
Drugbank ID	BE0008952
PharmGKB ID	PA29503

Target gene [HSPA4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009758	chr5	10	1		11	View
4010130	chr5	9	1		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HSPA4 expression and immune infiltrating cell level correlation result in HIV+ samples
HSPA4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of HSPA4 expression and immune infiltrating cell level correlation result in HIV+ samples
HSPA4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).