HIV Target gene Detail Information

> HSPA1L Gene Search Result

Gene Information

Gene Name	HSPA1L
Gene ID	3305
Gene Full Name	heat shock protein family A (Hsp70) member 1 like
Gene Alias	HSP70T; hum70t; HSP70-1L; HSP70-HOM
Transcripts	ENSG00000236251
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P34931
HGNC ID	HGNC:5234
VEGA ID	OTTHUMG00000004929
OMIM ID	140559
String ID	9606.ENSP00000364805
PharmGKB ID	PA29500

Target gene [HSPA1L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003221	chr6	66			66	View
4005293	chr6	29	5		34	View
4012769	chr6	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HSPA1L expression and immune infiltrating cell level correlation result in HIV+ samples
HSPA1L expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of HSPA1L expression and immune infiltrating cell level correlation result in HIV+ samples
HSPA1L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).