HBV Target gene Detail Information

> HSP90B1 Gene Search Result

Gene Information

Gene Name	HSP90B1
Gene ID	7184
Gene Full Name	heat shock protein 90 beta family member 1
Gene Alias	ECGP; GP96; TRA1; GRP94; HEL35; HEL-S-125m
Transcripts	ENSG00000166598
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P14625
HGNC ID	HGNC:12028
VEGA ID	OTTHUMG00000170118
OMIM ID	191175
String ID	9606.ENSP00000299767
Drugbank ID	BE0001165
PharmGKB ID	PA36705

Target gene [HSP90B1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006724	chr12	19	16		35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of HSP90B1 expression and immune infiltrating cell level correlation result in HBV+ samples
HSP90B1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).