HIV Target gene Detail Information

> HSF5 Gene Search Result

Gene Information

Gene Name	HSF5
Gene ID	124535
Gene Full Name	heat shock transcription factor 5
Gene Alias	HSF 5; HSTF 5
Transcripts	ENSG00000176160
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q4G112
HGNC ID	HGNC:26862
VEGA ID	OTTHUMG00000179078
String ID	9606.ENSP00000313243
PharmGKB ID	PA145008204

Target gene [HSF5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005125	chr17	18	17		35	View
4005530	chr17	17	14		31	View
4008343	chr17	13	2		15	View
4008770	chr17	1	13		14	View
4010203	chr17	6	3		9	View
4011066	chr17	7			7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HSF5 expression and immune infiltrating cell level correlation result in HIV+ samples
HSF5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).