HBV Target gene Detail Information

> HSF2BP Gene Search Result


Gene Information
Gene Name HSF2BP
Gene ID 11077
Gene Full Name heat shock transcription factor 2 binding protein
Transcripts ENSG00000160207
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O75031
HGNC ID HGNC:5226
VEGA ID OTTHUMG00000086863
OMIM ID 604554
String ID 9606.ENSP00000291560
PharmGKB ID PA29495
Target gene [HSF2BP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004048 chr21 24 54 17 95 View
1004669 chr21 71 2 73 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of HSF2BP expression and immune infiltrating cell level correlation result in HBV+ samples
HSF2BP expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).