HIV Target gene Detail Information

> HSF1 Gene Search Result

Gene Information

Gene Name	HSF1
Gene ID	3297
Gene Full Name	heat shock transcription factor 1
Gene Alias	HSTF1
Transcripts	ENSG00000284774
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q00613
HGNC ID	HGNC:5224
VEGA ID	OTTHUMG00000174604
OMIM ID	140580
String ID	9606.ENSP00000431512
Drugbank ID	BE0003514
PharmGKB ID	PA29493

Target gene [HSF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002845	chr8	70	2	5	77	View
4002846	chr8	70	2	5	77	View
4003982	chr8	45	4	2	51	View
4013375	chr8		3		3	View
4016107	chr8				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HSF1 expression and immune infiltrating cell level correlation result in HIV+ samples
HSF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).