HBV Target gene Detail Information

> HSD17B6 Gene Search Result

Gene Information

Gene Name	HSD17B6
Gene ID	8630
Gene Full Name	hydroxysteroid 17-beta dehydrogenase 6
Gene Alias	HSE; RODH; SDR9C6
Transcripts	ENSG00000025423
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	O14756
HGNC ID	HGNC:23316
VEGA ID	OTTHUMG00000170854
OMIM ID	606623
String ID	9606.ENSP00000451406
PharmGKB ID	PA142671671

Target gene [HSD17B6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009667	chr12	7	6	2	15	View
1012437	chr12	7			7	View
1012869	chr12	4		2	6	View
1013903	chr12	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of HSD17B6 expression and immune infiltrating cell level correlation result in HBV+ samples
HSD17B6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).