HBV Target gene Detail Information

> HS3ST2 Gene Search Result


Gene Information
Gene Name HS3ST2
Gene ID 9956
Gene Full Name heparan sulfate-glucosamine 3-sulfotransferase 2
Gene Alias 30ST2; 3OST2
Transcripts ENSG00000122254
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q9Y278
HGNC ID HGNC:5195
VEGA ID OTTHUMG00000094785
OMIM ID 604056
String ID 9606.ENSP00000261374
PharmGKB ID PA29468
Target gene [HS3ST2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012533 chr16 5 1 6 View
1013093 chr16 4 1 5 View
1403150 chr16 5 1 6 View
1403151 chr16 4 1 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of HS3ST2 expression and immune infiltrating cell level correlation result in HBV+ samples
HS3ST2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).