HTLV1 Target gene Detail Information

> HPGDS Gene Search Result

Gene Information

Gene Name	HPGDS
Gene ID	27306
Gene Full Name	hematopoietic prostaglandin D synthase
Gene Alias	GSTS; PGD2; PGDS; GSTS1; GSTS1-1
Transcripts	ENSG00000163106
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	O60760
HGNC ID	HGNC:17890
VEGA ID	OTTHUMG00000130974
OMIM ID	602598
String ID	9606.ENSP00000295256
Drugbank ID	BE0001167; BE0010006
PharmGKB ID	PA165664133

Target gene [HPGDS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6015915	chr4	2	6	5	13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of HPGDS expression and immune infiltrating cell level correlation result in HTLV1+ samples
HPGDS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).