HIV Target gene Detail Information

> HP1BP3 Gene Search Result

Gene Information

Gene Name	HP1BP3
Gene ID	50809
Gene Full Name	heterochromatin protein 1 binding protein 3
Gene Alias	HP1BP74; HP1-BP74
Transcripts	ENSG00000127483
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q5SSJ5
HGNC ID	HGNC:24973
VEGA ID	OTTHUMG00000002622
OMIM ID	616072
String ID	9606.ENSP00000312625
Drugbank ID	BE0009026; BE0009101
PharmGKB ID	PA142671673

Target gene [HP1BP3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004820	chr1	29	8	2	39	View
4006911	chr1	22			22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HP1BP3 expression and immune infiltrating cell level correlation result in HIV+ samples
HP1BP3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of HP1BP3 expression and immune infiltrating cell level correlation result in HIV+ samples
HP1BP3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).