HBV Target gene Detail Information

> HOPX Gene Search Result

Gene Information

Gene Name	HOPX
Gene ID	84525
Gene Full Name	HOP homeobox
Gene Alias	HOD; HOP; OB1; LAGY; TOTO; CAMEO; NECC1; SMAP31
Transcripts	ENSG00000171476
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	Q9BPY8
HGNC ID	HGNC:24961
VEGA ID	OTTHUMG00000128768
OMIM ID	607275
String ID	9606.ENSP00000450527
PharmGKB ID	PA162391564

Target gene [HOPX] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000808	chr4	750	341	316	1407	View
1008869	chr4	12	6	1	19	View
1011540	chr4	5	2	2	9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of HOPX expression and immune infiltrating cell level correlation result in HBV+ samples
HOPX expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).