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HIV Target gene Detail Information

> HNRNPC Gene Search Result


Gene Information
Gene Name HNRNPC
Gene ID 3183
Gene Full Name heterogeneous nuclear ribonucleoprotein C (C1/C2)
Gene Alias C1; C2; HNRNP; HNRPC; SNRPC
Transcripts ENSG00000092199
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P07910
HGNC ID HGNC:5035
VEGA ID OTTHUMG00000170757
OMIM ID 164020
String ID 9606.ENSP00000451291
PharmGKB ID PA162391217
Target gene [HNRNPC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000370 chr14 503 5 508 View
4002331 chr14 80 3 16 99 View
4002346 chr14 16 41 41 98 View
4004327 chr14 46 46 View
4004674 chr14 33 8 41 View
4007317 chr14 19 1 20 View
4007943 chr14 16 1 17 View
4009011 chr14 13 13 View
4012713 chr14 4 4 View
4013856 chr14 3 3 View
4015265 chr14 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of HNRNPC expression and immune infiltrating cell level correlation result in HIV+ samples
HNRNPC expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of HNRNPC expression and immune infiltrating cell level correlation result in HIV+ samples
HNRNPC expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).