HBV Target gene Detail Information

> HNF4G Gene Search Result


Gene Information
Gene Name HNF4G
Gene ID 3174
Gene Full Name hepatocyte nuclear factor 4 gamma
Gene Alias NR2A2; NR2A3
Transcripts ENSG00000164749
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytokinetic bridge;Cytosol;Mitotic spindle;
HPA Protein Class Info Nuclear receptors, Predicted intracellular proteins, Transcription factors
Uniport_ID Q14541
HGNC ID HGNC:5026
VEGA ID OTTHUMG00000149920
OMIM ID 605966
String ID 9606.ENSP00000379701
Drugbank ID BE0003179
PharmGKB ID PA29351
Target gene [HNF4G] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006591 chr8 28 8 36 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of HNF4G expression and immune infiltrating cell level correlation result in HBV+ samples
HNF4G expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).