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HBV Target gene Detail Information

> HNF1A Gene Search Result


Gene Information
Gene Name HNF1A
Gene ID 6927
Gene Full Name HNF1 homeobox A
Gene Alias HNF1; LFB1; TCF1; HNF4A; MODY3; TCF-1; HNF-1A; IDDM20
Transcripts ENSG00000135100
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins
HGNC ID HGNC:11621
VEGA ID OTTHUMG00000151015
OMIM ID 142410
String ID 9606.ENSP00000257555
Drugbank ID BE0004514
PharmGKB ID PA36380
Target gene [HNF1A] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 16099903 A1899G
PreC
G
R
S
C
 View
2 16099903 G1896A
PreC
G
R
S
C
 View

Target gene [HNF1A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004540 chr12 39 27 12 78 View
1008830 chr3 3 1 15 19 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of HNF1A expression and immune infiltrating cell level correlation result in HBV+ samples
HNF1A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).