HIV Target gene Detail Information

> HMCES Gene Search Result

Gene Information

Gene Name	HMCES
Gene ID	56941
Gene Full Name	5-hydroxymethylcytosine binding, ES cell specific
Gene Alias	DC12; SRAPD1; C3orf37
Transcripts	ENSG00000183624
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96FZ2
HGNC ID	HGNC:24446
VEGA ID	OTTHUMG00000159452
OMIM ID	618288
String ID	9606.ENSP00000372955
PharmGKB ID	PA142672398

Target gene [HMCES] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007679	chr3	18			18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HMCES expression and immune infiltrating cell level correlation result in HIV+ samples
HMCES expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).