HIV Target gene Detail Information

> HK1 Gene Search Result

Gene Information

Gene Name	HK1
Gene ID	3098
Gene Full Name	hexokinase 1
Gene Alias	HK; HKD; HKI; HXK1; RP79; HMSNR; HK1-ta; HK1-tb; HK1-tc; hexokinase
Transcripts	ENSG00000156515
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P19367
HGNC ID	HGNC:4922
VEGA ID	OTTHUMG00000018380
OMIM ID	142600
String ID	9606.ENSP00000402103
Drugbank ID	BE0001108
PharmGKB ID	PA29300

Target gene [HK1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008657	chr10	14			14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HK1 expression and immune infiltrating cell level correlation result in HIV+ samples
HK1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of HK1 expression and immune infiltrating cell level correlation result in HIV+ samples
HK1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).