HIV Target gene Detail Information

> HIPK1 Gene Search Result

Gene Information

Gene Name	HIPK1
Gene ID	204851
Gene Full Name	homeodomain interacting protein kinase 1
Gene Alias	Myak; Nbak2
Transcripts	ENSG00000163349
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Centrosome;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q86Z02
HGNC ID	HGNC:19006
VEGA ID	OTTHUMG00000011983
OMIM ID	608003
String ID	9606.ENSP00000358571
PharmGKB ID	PA134897980

Target gene [HIPK1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006517	chr1	20	2	2	24	View
4007488	chr1	16	3		19	View
4010813	chr1	7	1		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HIPK1 expression and immune infiltrating cell level correlation result in HIV+ samples
HIPK1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).