HTLV1 Target gene Detail Information

> HHAT Gene Search Result

Gene Information

Gene Name	HHAT
Gene ID	55733
Gene Full Name	hedgehog acyltransferase
Gene Alias	Skn; SKI1; MART2
Transcripts	ENSG00000280680
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q5VTY9
HGNC ID	HGNC:18270
VEGA ID	OTTHUMG00000036447
OMIM ID	605743
String ID	9606.ENSP00000438468
PharmGKB ID	PA134926499

Target gene [HHAT] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005307	chr1	32	23	35	90	View
6011812	chr1	14	6	5	25	View
6014141	chr1	5	11	1	17	View
6021319	chr1	5		1	6	View
6028317	chr1	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of HHAT expression and immune infiltrating cell level correlation result in HTLV1+ samples
HHAT expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of HHAT expression and immune infiltrating cell level correlation result in HTLV1+ samples
HHAT expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of HHAT expression and immune infiltrating cell level correlation result in HTLV1+ samples
HHAT expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).