HBV Target gene Detail Information

> HGSNAT Gene Search Result

Gene Information

Gene Name	HGSNAT
Gene ID	138050
Gene Full Name	heparan-alpha-glucosaminide N-acetyltransferase
Gene Alias	RP73; HGNAT; MPS3C; TMEM76
Transcripts	ENSG00000165102
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q68CP4
HGNC ID	HGNC:26527
VEGA ID	OTTHUMG00000164102
OMIM ID	610453
String ID	9606.ENSP00000368965
PharmGKB ID	PA162390851

Target gene [HGSNAT] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010420	chr8	12			12	View
1400175	chr8	434	30	67	531	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of HGSNAT expression and immune infiltrating cell level correlation result in HBV+ samples
HGSNAT expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).