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HBV Target gene Detail Information

> HFM1 Gene Search Result


Gene Information
Gene Name HFM1
Gene ID 164045
Gene Full Name HFM1, ATP dependent DNA helicase homolog
Gene Alias MER3; POF9; Si-11; SEC63D1; Si-11-6; helicase
Transcripts ENSG00000162669
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;Vesicles;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID A2PYH4
HGNC ID HGNC:20193
VEGA ID OTTHUMG00000010093
OMIM ID 615684
String ID 9606.ENSP00000359454
PharmGKB ID PA142671690
Target gene [HFM1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002134 chr1 314 5 15 334 View
1002568 chr1 224 8 13 245 View
1003319 chr1 128 3 14 145 View
1019118 chr1 0 View
1401396 chr1 314 5 15 334 View
1403136 chr1 224 8 13 245 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of HFM1 expression and immune infiltrating cell level correlation result in HBV+ samples
HFM1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).