HIV Target gene Detail Information

> HERPUD1 Gene Search Result

Gene Information

Gene Name	HERPUD1
Gene ID	9709
Gene Full Name	homocysteine inducible ER protein with ubiquitin like domain 1
Gene Alias	SUP; HERP; Mif1
Transcripts	ENSG00000051108
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q15011
HGNC ID	HGNC:13744
VEGA ID	OTTHUMG00000133276
OMIM ID	608070
String ID	9606.ENSP00000409555
PharmGKB ID	PA29252

Target gene [HERPUD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001224	chr16	55	84	52	191	View
4003520	chr16	16	41	3	60	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HERPUD1 expression and immune infiltrating cell level correlation result in HIV+ samples
HERPUD1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of HERPUD1 expression and immune infiltrating cell level correlation result in HIV+ samples
HERPUD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).