HBV Target gene Detail Information

> HEPHL1 Gene Search Result


Gene Information
Gene Name HEPHL1
Gene ID 341208
Gene Full Name hephaestin like 1
Transcripts ENSG00000181333
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID Q6MZM0
HGNC ID HGNC:30477
VEGA ID OTTHUMG00000167751
OMIM ID 618455
String ID 9606.ENSP00000313699
Drugbank ID BE0005863; BE0005816
PharmGKB ID PA134873144
Target gene [HEPHL1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1018366 chr11 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of HEPHL1 expression and immune infiltrating cell level correlation result in HBV+ samples
HEPHL1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).