HIV Target gene Detail Information

> HELB Gene Search Result

Gene Information

Gene Name	HELB
Gene ID	92797
Gene Full Name	DNA helicase B
Gene Alias	DHB; hDHB
Transcripts	ENSG00000127311
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q8NG08
HGNC ID	HGNC:17196
VEGA ID	OTTHUMG00000169006
OMIM ID	614539
String ID	9606.ENSP00000247815
PharmGKB ID	PA134987279

Target gene [HELB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005817	chr12	29			29	View
4014850	chr12	2			2	View
4014851	chr12	2			2	View
4014852	chr12	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HELB expression and immune infiltrating cell level correlation result in HIV+ samples
HELB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).