HIV Target gene Detail Information

> HECTD4 Gene Search Result

Gene Information

Gene Name	HECTD4
Gene ID	283450
Gene Full Name	HECT domain E3 ubiquitin protein ligase 4
Gene Alias	HEEL; POTAGE; C12ord51; C12orf51
Transcripts	ENSG00000173064
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
HGNC ID	HGNC:26611
VEGA ID	OTTHUMG00000150719
String ID	9606.ENSP00000449784
PharmGKB ID	PA143485380

Target gene [HECTD4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008808	chr12	11	2	1	14	View
4012880	chr12	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HECTD4 expression and immune infiltrating cell level correlation result in HIV+ samples
HECTD4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).