HIV Target gene Detail Information

> HECTD1 Gene Search Result

Gene Information

Gene Name	HECTD1
Gene ID	25831
Gene Full Name	HECT domain E3 ubiquitin protein ligase 1
Gene Alias	EULIR
Transcripts	ENSG00000092148
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9ULT8
HGNC ID	HGNC:20157
VEGA ID	OTTHUMG00000170670
OMIM ID	618649
String ID	9606.ENSP00000382269
PharmGKB ID	PA134989284

Target gene [HECTD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010003	chr14	3	7		10	View
4014372	chr14	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HECTD1 expression and immune infiltrating cell level correlation result in HIV+ samples
HECTD1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of HECTD1 expression and immune infiltrating cell level correlation result in HIV+ samples
HECTD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).