HTLV1 Target gene Detail Information

> HEBP1 Gene Search Result


Gene Information
Gene Name HEBP1
Gene ID 50865
Gene Full Name heme binding protein 1
Gene Alias HBP; HEBP
Transcripts ENSG00000013583
Virus HTLV1
Gene Type protein coding
HPA Location Info Vesicles;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9NRV9
HGNC ID HGNC:17176
VEGA ID OTTHUMG00000168771
OMIM ID 605826
String ID 9606.ENSP00000014930
PharmGKB ID PA29236
Target gene [HEBP1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6014048 chr12 17 17 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of HEBP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
HEBP1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of HEBP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
HEBP1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of HEBP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
HEBP1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).