HIV Target gene Detail Information

> HDAC8 Gene Search Result

Gene Information

Gene Name	HDAC8
Gene ID	55869
Gene Full Name	histone deacetylase 8
Gene Alias	HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1
Transcripts	ENSG00000147099
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID	Q9BY41
HGNC ID	HGNC:13315
VEGA ID	OTTHUMG00000021814
OMIM ID	300269
String ID	9606.ENSP00000362674
Drugbank ID	BE0001608; BE0008667
PharmGKB ID	PA37766

Target gene [HDAC8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016452	chrX				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HDAC8 expression and immune infiltrating cell level correlation result in HIV+ samples
HDAC8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).