HIV Target gene Detail Information

> HDAC8 Gene Search Result


Gene Information
Gene Name HDAC8
Gene ID 55869
Gene Full Name histone deacetylase 8
Gene Alias HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1
Transcripts ENSG00000147099
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Plasma membrane;
HPA Protein Class Info Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID Q9BY41
HGNC ID HGNC:13315
VEGA ID OTTHUMG00000021814
OMIM ID 300269
String ID 9606.ENSP00000362674
Drugbank ID BE0001608; BE0008667
PharmGKB ID PA37766
Target gene [HDAC8] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4016452 chrX 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of HDAC8 expression and immune infiltrating cell level correlation result in HIV+ samples
HDAC8 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).