HIV Target gene Detail Information

> HDAC10 Gene Search Result

Gene Information

Gene Name	HDAC10
Gene ID	83933
Gene Full Name	histone deacetylase 10
Gene Alias	HD10
Transcripts	ENSG00000100429
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q969S8
HGNC ID	HGNC:18128
VEGA ID	OTTHUMG00000044647
OMIM ID	608544
String ID	9606.ENSP00000216271
Drugbank ID	BE0003526; BE0009579; BE0008667
PharmGKB ID	PA38297

Target gene [HDAC10] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002304	chr22	99	1		100	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HDAC10 expression and immune infiltrating cell level correlation result in HIV+ samples
HDAC10 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).