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HTLV1 Target gene Detail Information

> HAO1 Gene Search Result


Gene Information
Gene Name HAO1
Gene ID 54363
Gene Full Name hydroxyacid oxidase 1
Gene Alias GOX; GOX1; HAOX1
Transcripts ENSG00000101323
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q9UJM8
HGNC ID HGNC:4809
VEGA ID OTTHUMG00000031841
OMIM ID 605023
String ID 9606.ENSP00000368066
Drugbank ID BE0003766
PharmGKB ID PA29185
Target gene [HAO1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6012730 chr20 21 21 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of HAO1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
HAO1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of HAO1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
HAO1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of HAO1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
HAO1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).