HIV Target gene Detail Information

> HAGH Gene Search Result

Gene Information

Gene Name	HAGH
Gene ID	3029
Gene Full Name	hydroxyacylglutathione hydrolase
Gene Alias	GLO2; GLX2; GLXII; HAGH1
Transcripts	ENSG00000063854
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q16775
HGNC ID	HGNC:4805
VEGA ID	OTTHUMG00000128662
OMIM ID	138760
String ID	9606.ENSP00000380514
Drugbank ID	BE0001825
PharmGKB ID	PA29179

Target gene [HAGH] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011982	chr16	5	1		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of HAGH expression and immune infiltrating cell level correlation result in HIV+ samples
HAGH expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of HAGH expression and immune infiltrating cell level correlation result in HIV+ samples
HAGH expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).