HTLV1 Target gene Detail Information

> HADH Gene Search Result

Gene Information

Gene Name	HADH
Gene ID	3033
Gene Full Name	hydroxyacyl-CoA dehydrogenase
Gene Alias	HAD; HCDH; HHF4; HADH1; SCHAD; HADHSC; MSCHAD
Transcripts	ENSG00000138796
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q16836
HGNC ID	HGNC:4799
VEGA ID	OTTHUMG00000131810
OMIM ID	601609
String ID	9606.ENSP00000474560
Drugbank ID	BE0000377
PharmGKB ID	PA29173

Target gene [HADH] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6006215	chr4	61	12		73	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of HADH expression and immune infiltrating cell level correlation result in HTLV1+ samples
HADH expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of HADH expression and immune infiltrating cell level correlation result in HTLV1+ samples
HADH expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).