HBV Target gene Detail Information

> GYS2 Gene Search Result


Gene Information
Gene Name GYS2
Gene ID 2998
Gene Full Name glycogen synthase 2
Transcripts ENSG00000111713
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID P54840
HGNC ID HGNC:4707
VEGA ID OTTHUMG00000169135
OMIM ID 138571
String ID 9606.ENSP00000261195
PharmGKB ID PA29085
Target gene [GYS2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006074 chr12 24 13 7 44 View
1013534 chr12 5 5 View
1018763 chr12 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GYS2 expression and immune infiltrating cell level correlation result in HBV+ samples
GYS2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).