HBV Target gene Detail Information

> GUCY1A2 Gene Search Result

Gene Information

Gene Name	GUCY1A2
Gene ID	2977
Gene Full Name	guanylate cyclase 1 soluble subunit alpha 2
Gene Alias	GC-SA2; GUC1A2
Transcripts	ENSG00000152402
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID	P33402
HGNC ID	HGNC:4684
VEGA ID	OTTHUMG00000166296
OMIM ID	601244
String ID	9606.ENSP00000282249
Drugbank ID	BE0003578
PharmGKB ID	PA186

Target gene [GUCY1A2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009981	chr11	1	5	8	14	View
1013061	chr11	2	2	1	5	View
1019310	chr11				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GUCY1A2 expression and immune infiltrating cell level correlation result in HBV+ samples
GUCY1A2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).