HIV Target gene Detail Information

> GTPBP3 Gene Search Result

Gene Information

Gene Name	GTPBP3
Gene ID	84705
Gene Full Name	GTP binding protein 3, mitochondrial
Gene Alias	MSS1; MTGP1; THDF1; GTPBG3; COXPD23
Transcripts	ENSG00000130299
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q969Y2
HGNC ID	HGNC:14880
VEGA ID	OTTHUMG00000182766
OMIM ID	608536
String ID	9606.ENSP00000351644
PharmGKB ID	PA134883205

Target gene [GTPBP3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004875	chr19	38			38	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GTPBP3 expression and immune infiltrating cell level correlation result in HIV+ samples
GTPBP3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GTPBP3 expression and immune infiltrating cell level correlation result in HIV+ samples
GTPBP3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).