HBV Target gene Detail Information

> GTF2I Gene Search Result

Gene Information

Gene Name	GTF2I
Gene ID	2969
Gene Full Name	general transcription factor IIi
Gene Alias	WBS; DIWS; SPIN; IB291; BAP135; BTKAP1; TFII-I; WBSCR6; GTFII-I
Transcripts	ENSG00000263001
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P78347
HGNC ID	HGNC:4659
VEGA ID	OTTHUMG00000156237
OMIM ID	601679
String ID	9606.ENSP00000460070
PharmGKB ID	PA29045

Target gene [GTF2I] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001744	chr7	15	408	83	506	View
1001884	chr7	15	376	45	436	View
1003764	chr7	19	56	36	111	View
1004085	chr7	23	53	18	94	View
1005745	chr7	45	4		49	View
1006399	chr7	10	24	5	39	View
1007062	chr7	12	18	1	31	View
1007448	chr7	20	7		27	View
1007794	chr7	23	1		24	View
1008148	chr7	18	4		22	View
1008643	chr7	20			20	View
1008658	chr7	16	4		20	View
1009171	chr7	15	2		17	View
1009857	chr7	12	2		14	View
1010022	chr7	10	3		13	View
1010264	chr7	10	3		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GTF2I expression and immune infiltrating cell level correlation result in HBV+ samples
GTF2I expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).